COMPARATIVE STUDY OF FENTANYL, TRAMADOL AND NALBUPHINE IN ATTENUATION OF HAEMODYNAMIC RESPONSES IN LAPAROSCOPIC CHOLECYSTECTOMY

Background:-Numerous attempts have been made in the past to attenuate haemodynamic responses occurring during laparoscopic cholecystectomy. The present study compared effect of three opioids namely TRAMADOL, Fentanyl and Nalbuphine obtundation cholecystectomy terms Heart rate, BP (SBP, DBP MAP) secondary aim was calculate duration analgesia sedation score. Materials And Methods:-This a randomised comparing opioid drugs- nalbuphine, fentanyl TRAMADOL. It carried out on 75 patients either sex aged 18 - 60 years scheduled for elective under GA. Subjects were enrolled into groups- Group B (n= 25) received inj. TRAMADOL 2 mcg/kg IV, F IV N 0.2 mg/kg 5 minutes before induction. Result:-At time extubation, mean MAP B, 99.88, 95.32 97.24 respectively. This difference is highly significant when statistically (p value 0.005). Conclusion:-With this study, we conclude that administration intravenous nalbuphine five prior induction anaesthesia helps better than